Tumor de células granulares de localización atípica
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Universidad Industrial de Santander
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El Tumor de células granulares es una neoplasia infrecuente, generalmente benigna, que suele afectar cara y cuello. Aparece entre la segunda y la sexta década, más frecuentemente en la raza negra y en mujeres. El 25% de los casos presenta lesiones múltiples. El único tratamiento es quirúrgico. Un varón de 17 años presentó una lesión nodular única epitroclear en el codo derecho. Se realizó una escisión amplia y el resultado anatomopatológico fue un tumor de células granulares. Tras un seguimiento de seis meses no hay evidencia de recidiva. La patogénesis debe ser claramente establecida, aunque la literatura sostiene la hipótesis de que tiene su origen en las células de Schwann. Los autores subrayan la peculiaridad de la localización epitroclear y discuten la clasificación, fisiopatología y el tratamiento del tumor con una revisión de la literatura. (MÉD.UIS. 2011;24(3):283-6).Palabras clave: Cáncer. Tumor de células granulares. Inmunohistoquímica.
Granular cell tumor in unusual location.Granular cell tumor is an infrequent neoplasm, benign in most of the cases, that usually affects head and neck. It develops between the second and sixth decades of life, more frequently among women and black people. 25% of the cases occur as multiple lesions. The only treatment is surgery. A 17- year old male presented a nodular, single and firm epithroclear lesion in his right elbow. A wide surgical excision was performed and the final pathologic diagnosis was granular cell tumor. During follow-up of six months there is no evidence of tumour recurrence. The pathogenesis of the tumor has still to be clearly established, although literature sustains the hypothesis that it has origin in the Schwann´s cells. The authors underscore the peculiarity of the epithroclear localization and discuss the classification, pathophysiology and the treatment of Abrikossoff´s tumor through a review of the literature. (MÉD.UIS. 2011;24(3):283-6).Key words: Cancer. Granular cell tumor. Inmunohistochemistry.
Granular cell tumor in unusual location.Granular cell tumor is an infrequent neoplasm, benign in most of the cases, that usually affects head and neck. It develops between the second and sixth decades of life, more frequently among women and black people. 25% of the cases occur as multiple lesions. The only treatment is surgery. A 17- year old male presented a nodular, single and firm epithroclear lesion in his right elbow. A wide surgical excision was performed and the final pathologic diagnosis was granular cell tumor. During follow-up of six months there is no evidence of tumour recurrence. The pathogenesis of the tumor has still to be clearly established, although literature sustains the hypothesis that it has origin in the Schwann´s cells. The authors underscore the peculiarity of the epithroclear localization and discuss the classification, pathophysiology and the treatment of Abrikossoff´s tumor through a review of the literature. (MÉD.UIS. 2011;24(3):283-6).Key words: Cancer. Granular cell tumor. Inmunohistochemistry.