La adaptación biológica heredable: avances y novedades
No Thumbnail Available
Date
Authors
Advisors
Evaluators
Journal Title
Journal ISSN
Volume Title
Publisher
Universidad Industrial de Santander
Abstract
Description
OBJETIVOS: el presente artículo se propone repasar los avances más recientes realizados en epigenética.
FUENTE DE LOS DATOS: revisión no sistemática de la literatura, para obtener referencias pertinentes y actualizadas relacionadas con el tema.
SÍNTESIS DE LOS DATOS: los estudios analizados ponen especial énfasis en los procesos de metilación, modifcación de histonas y la acción de ARN no codifcante, como mecanismos fundamentales para que ocurran los cambios fenotípicos heredables por efecto ambiental, con fnes de adaptación.
CONCLUSIONES: el entendimiento de estos factores podría revolucionar el enfoque de la biología evolutiva y del desarrollo; y su aplicación a las ciencias médicas determinará sin duda un nuevo abordaje a los conceptos de salud y enfermedad.
Palabras clave: Epigenética. Genotipo. Fenotipo.
OBJECTIVES: to present the most recent advances made in epigenetics research. SOURCES: Non-systematic review of the literature, in order to obtain relevant and updated references related to the subject. SUMMARY OF FINDINGS: studies remarks methylation, histone modifcation, and the action of non-coding RNA processes, as key mechanisms to occur phenotypic changes by hereditable environmental effects. CONCLUSIONS: the knowledge of these factors could change the approach of developmental and evolutionary biology, and its applications to medical science with a new approach to the concepts of health and disease. Key words: Epigenetics. Genotype. Phenotype.
OBJECTIVES: to present the most recent advances made in epigenetics research. SOURCES: Non-systematic review of the literature, in order to obtain relevant and updated references related to the subject. SUMMARY OF FINDINGS: studies remarks methylation, histone modifcation, and the action of non-coding RNA processes, as key mechanisms to occur phenotypic changes by hereditable environmental effects. CONCLUSIONS: the knowledge of these factors could change the approach of developmental and evolutionary biology, and its applications to medical science with a new approach to the concepts of health and disease. Key words: Epigenetics. Genotype. Phenotype.