Caracterización eléctrica de tejido endocervical para determinar lesión neoplásica de cuello uterino

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dc.contributor.advisorMiranda Mercado, David Alejandro
dc.contributor.advisorGonzález Correa, Carlos Augusto
dc.contributor.authorCorzo Mantilla, Sandra Patricia
dc.date.accessioned2024-03-03T20:51:20Z
dc.date.available2014
dc.date.available2024-03-03T20:51:20Z
dc.date.created2014
dc.date.issued2014
dc.description.abstractEl cáncer de cuello uterino es considerado un problema de salud pública en el mundo. Esta enfermedad avanza gradualmente, y en sus primeras etapas es posible revertirla. Sin embargo, sus síntomas solo se presentan cuando el grado de lesión es muy alto.
dc.description.abstractenglishCervical cancer is considered a public health problem in the world. This disease progresses gradually, and in early stages is possible to reverse it. However, symptoms only occur at very high degree of lesion. In developed countries the incidence and mortality rates have been reduced through campaigns that promote regular cervical cytology. Unfortunately, in developing countries, this technique has not have the expected impact. The lack of coverage and poor quality of taking and reading the samples are the main reasons. In response to this problem CIMBIOS, our investigation group, has developed a set of research towards implementing an early detection technique for cervical cancer, based on electrical impedance spectroscopy (EIS). Furthermore, with high sensitivity and specificity, low cost and real-time results. According to above, the present investigation was propose in order to study the electrical properties of endocervix by electrical impedance spectra measured on the exocervix. In this way, the electrical impedance spectrum of ex vivo fresh pieces of uteri taken from hysterectomy, were measured by altering the electrical properties of the endocervix using conductive bars. Data were analyzed according to Cole-Cole model with multiple dispersions and additionally, a physical-mathematical model of electrical properties of tissue. Based on the generalized effective medium theory of induced polarization (GEMTIP), this model shows a clear relationship between electrical and biochemical properties of the tissue. The results suggest that electrical properties in neoplastic tissue are associated to carcinogenic field effect
dc.description.degreelevelMaestría
dc.description.degreenameMagíster en Física
dc.format.mimetypeapplication/pdf
dc.identifier.instnameUniversidad Industrial de Santander
dc.identifier.reponameUniversidad Industrial de Santander
dc.identifier.repourlhttps://noesis.uis.edu.co
dc.identifier.urihttps://noesis.uis.edu.co/handle/20.500.14071/31341
dc.language.isospa
dc.publisherUniversidad Industrial de Santander
dc.publisher.facultyFacultad de Ciencias
dc.publisher.programMaestría en Física
dc.publisher.schoolEscuela de Física
dc.rightshttp://creativecommons.org/licenses/by/4.0/
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
dc.rights.licenseAttribution-NonCommercial 4.0 International (CC BY-NC 4.0)
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0
dc.subjectEspectroscopia
dc.subjectImpedancia Eléctrica
dc.subjectCáncer
dc.subjectEndocérvix.
dc.subject.keywordSpectroscopy
dc.subject.keywordElectrical Impedance
dc.subject.keywordCancer
dc.subject.keywordEndocervix
dc.subject.keywordExocervix.
dc.titleCaracterización eléctrica de tejido endocervical para determinar lesión neoplásica de cuello uterino
dc.title.englishElectrical characterization of tissue to determine endocervical neoplastic lesion.
dc.type.coarhttp://purl.org/coar/version/c_b1a7d7d4d402bcce
dc.type.hasversionhttp://purl.org/coar/resource_type/c_bdcc
dc.type.localTesis/Trabajo de grado - Monografía - Maestria
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