Factores de riesgo asociados a síndrome de apnea hipopnea obstructiva del sueño en una cohorte de pacientes sometidos a polisomnografía
dc.contributor.advisor | Bolivar Grimaldos, Fabio | |
dc.contributor.author | Mendoza Herrera, Tania | |
dc.date.accessioned | 2024-03-03T22:50:59Z | |
dc.date.available | 2016 | |
dc.date.available | 2024-03-03T22:50:59Z | |
dc.date.created | 2016 | |
dc.date.issued | 2016 | |
dc.description.abstract | El Síndrome de Apnea/Hipopnea obstructiva del sueño (SAHOS) es un desorden crónico de colapso repetitivo parcial/completo de la vía aérea. Ocasiona desaturación intermitente, fragmentación, ronquidos durante el sueño y somnolencia diurna relacionada con eventos adversos (RCV/complicación pop). Prevalencia mundial (1.27.5%), Colombia (H:4-6%:M:2-4%). Establecer factores de riesgo regionales contribuye con predicción local. Objetivo general: Determinar factores de riesgo asociados a SAHOS en sujetos con hipersomnia sometidos a Polisomnografía en Bucaramanga/Santander. Metodología: Estudio observacional analítico tipo corte transversal. Muestreo no probabilístico. Casos concurrentes(n=175), >18 años captados entre nov./2014-oct/2015 (INO). Variables: clínicas, antropométricas, escalas de Epworth/Berlín/Pittsburg. Exclusión: Discapacidad física/mental, Medicamentos/drogas psicoactivas, ocupación que altere patrón del sueño, embarazadas, viajes semana previa (diferente zona horaria) y tratamiento para SAHOS. Análisis descriptivo, bivariado y curvas ROC/sensibilidad/especificidad Escala Berlín. Resultados: Edad: 56,3+/-13,52_años(H=103;55,47+/-13,96;M=72;57,48+/-12,87, Mayor Edad SAHOS_Severo). Mayor Obesidad/HTA en SAHOS. Tabaquismo pasivo (29.71%: Mayor en Hombres y SAHOS_Moderado/severo(SMS)), Peso(85.73+/-20.56_kg;>Hombres,>SMS), IMC (31.88+/-6.87_kg./mts2), Perímetro cuello(41.84+/-4.94_cms;>SMS), Perímetro abdominal(105,91+/-16.60 cms;>SMS). Escala Pittsburg(10.17+/-3.32_ptos;>SMS). Índice Epworth(11.29+/-6.56_ptos;>SMS). Algún grado Hipersomnia (73.82%), SAHOS según Berlín (83.89%). Bivariado: Obesidad (OR:2.6;IC95%:1.0681-6.3710;p=0.03), HTA (OR:2.6;IC95%:1,0681-6,3710;p=0.03), Edad>55_años (OR:3.04;IC95%:1.2735-7.2981; p=0.01), Peso>89_kg (OR:2.83;IC95%:1.0120-7.9215;p=0.04), Talla>152_cms (OR:3.13;IC95%:1.0709-9.1975;p=0.03), IMC>29_kg./mts2(OR:2.80;IC95%:1.1717-6.6996;p=0.02), Perímetro_cuello>38cm (OR:2.58;IC95%:1.0640-6.2857;p=0.03), Perímetro abdominal>107cm. (OR:3.11;IC95%:1,1848-8,1995; p=0.02), Eficiencia del sueño por PSG>47% (OR:0.25;IC95%:0.0718-0.8746; p=0.03) y SO2>78%(OR:6.35;IC95%:1,2074-33,3722; p=0.03) se asocian significativamente con IAH>5, diagnóstico de SAHOS. Berlín: Sensibilidad 100%, Clasificación correcta 85.14% (AUC=0.5968) Conclusión: Comparado con literatura mundial, presencia de SAHOS a menor edad, con similares factores de riesgo (RCV, antropometría), Hipersomnia por Epworth no asociada, Pobre discriminación con Berlín. Importante asociación con variables antropométricas como línea de base para la construcción de modelo de predicción local. | |
dc.description.abstractenglish | Risk factors associated with obstructive sleep apnea/hypopnea syndrome in a cohort of patients undergoing polysomnography | |
dc.description.degreelevel | Especialización | |
dc.description.degreename | Especialista en Medicina Interna | |
dc.format.mimetype | application/pdf | |
dc.identifier.instname | Universidad Industrial de Santander | |
dc.identifier.reponame | Universidad Industrial de Santander | |
dc.identifier.repourl | https://noesis.uis.edu.co | |
dc.identifier.uri | https://noesis.uis.edu.co/handle/20.500.14071/35542 | |
dc.language.iso | spa | |
dc.publisher | Universidad Industrial de Santander | |
dc.publisher.faculty | Facultad de Salud | |
dc.publisher.program | Especialización en Medicina Interna | |
dc.publisher.school | Escuela de Medicina | |
dc.rights | http://creativecommons.org/licenses/by/4.0/ | |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | |
dc.rights.creativecommons | Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) | |
dc.rights.license | Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0 | |
dc.subject | Síndrome De Apnea/Hipopnea Obstructiva Del Sueño | |
dc.subject | Factor De Riesgo | |
dc.subject | Polisomnografía | |
dc.subject | Corte Transversal. | |
dc.subject.keyword | Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) is a chronic disorder of partial / full repetitive collapse of the airway. It causes intermittent desaturation | |
dc.subject.keyword | fragmentation | |
dc.subject.keyword | snoring during sleep and daytime sleepiness associated with adverse events (CVR / POP complication). Global prevalence (1.2% 7.5%) | |
dc.subject.keyword | Colombia (H: 4-6%: M: 2-4%). Establishing regional risk factors contributes to the local prediction. Objective: To determine risk factors associated with OSAHS in patients with hypersomnia underwent polysomnography in Bucaramanga / Santander. Methodology: Observational analytical cross sectional study. Non-probability concurrent sampling. (n = 175) | |
dc.subject.keyword | >18 years captured between nov./2014-oct/2015 (INO). Variables: Clinical | |
dc.subject.keyword | anthropometric | |
dc.subject.keyword | Epworth scales/Berlin/Pittsburg. Exclusion: physical/mental disability | |
dc.subject.keyword | drugs/psychoactive drugs | |
dc.subject.keyword | occupation altering sleep patterns | |
dc.subject.keyword | pregnancy | |
dc.subject.keyword | trips in previous week (different time zone) and treatment for OSAHS. Descriptive analysis | |
dc.subject.keyword | bivariate and ROC curves / sensitivity / specificity scale Berlin. Results: Age: 56.3 +/- 13 | |
dc.subject.keyword | 52_years (Male= 103; 55.47 +/- 13.96; Female= 72; 57.48 +/- 12.87 | |
dc.subject.keyword | Elderly Severe OSAHS). Mayor Obesity / HTA in OSAHS. Passive smoking (29.71%: higher in men and Moderate/severe OSAHS (MSO)) | |
dc.subject.keyword | weight (85.73 +/- 20.56_kg;> Men-MSO) | |
dc.subject.keyword | BMI (31.88 +/- 6.87_kg./mts2) | |
dc.subject.keyword | neck circumference (4.94_cms +/- 41.84;> MSO) | |
dc.subject.keyword | abdominal circumference (105.91 +/- 16.60 cms;>MSO). Scale Pittsburg (10.17 +/- 3.32_ptos;>MSO). Epworth index (11.29 +/- 6.56_ptos;>MSO). Some degree hypersomnia (73.82%) | |
dc.subject.keyword | OSAHS according Berlin (83.89%). Bivariate: Obesity (OR: 2.6; 95% CI: 1.0681-6.3710; p=0.03) | |
dc.subject.keyword | hypertension (OR: 2.6; 95% CI | |
dc.subject.keyword | 1.0681 to 6.3710; p=0.03) | |
dc.subject.keyword | Age> 55_years (OR: 3.04; 95% CI: 1.2735-7.2981; p=0.01) | |
dc.subject.keyword | weight> 89_kg (OR: 2.83; 95% CI: 1.0120-7.9215; p = 0.04) | |
dc.subject.keyword | Height> 152_cms (OR: 3.13; 95% CI: 1.0709-9.1975; p=0.03 ) | |
dc.subject.keyword | BMI>29_kg./mts2 (OR: 2.80; 95% CI: 1.1717-6.6996; p=0.02) | |
dc.subject.keyword | Neck perimeter> 38 cms. (OR: 2.58; 95% CI: 1.0640-6.2857; p=0.03) | |
dc.subject.keyword | abdominal circumference>107cm. (OR: 3.11; 95% CI | |
dc.subject.keyword | 1.1848-8.1995; p=0.02) | |
dc.subject.keyword | PSG sleep efficiency>47% (OR: 0.25; 95% CI | |
dc.subject.keyword | 0.0718-0.8746; p=0.03) and SO2>78% (OR: 6.35; 95% CI: 1.2074-33.3722; p=0.03) were significantly associated with AHI> 5 | |
dc.subject.keyword | diagnosis of OSAHS. Berlin: sensitivity 100% | |
dc.subject.keyword | correct classification 85.14% (AUC=0.5968) Conclusion: Compared to world literature | |
dc.subject.keyword | the presence of OSAHS at a younger age | |
dc.subject.keyword | with similar risk factors (RCV | |
dc.subject.keyword | anthropometry) | |
dc.subject.keyword | hypersomnia by Epworth not associated with Berlin Poor discrimination. Important association with anthropometric variables as the baseline for building local prediction model. | |
dc.title | Factores de riesgo asociados a síndrome de apnea hipopnea obstructiva del sueño en una cohorte de pacientes sometidos a polisomnografía | |
dc.title.english | Obstructive Sleep Apnea/Hypopnea Syndrome, Risk Factor, Polysomnography, Cross-Sectional. | |
dc.type.coar | http://purl.org/coar/version/c_b1a7d7d4d402bcce | |
dc.type.hasversion | http://purl.org/coar/resource_type/c_7a1f | |
dc.type.local | Tesis/Trabajo de grado - Monografía - Pregrado |
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